objective(s): pregabalin (pgb) is a new antiepileptic drug that has received fda approval for patient who suffers from central neuropathic pain, partial seizures, generalized anxiety disorder, fibromyalgia and sleep disorders. this study was undertaken to evaluate the possible adverse effects of pgb on the muscular system of mice. materials and methods: to evaluate the effect of pgb on skeletal...

objective(s):in this study, we aimed at evaluation of electrophysiological and histopathalogical characteristics of statin-induced muscle injury as well as clinical features of patients who develop this condition in terms of frequency and pattern of evolution. materials and methods: forty patients (age 39-74 years) including 25 subjects with type 2 diabetes mellitus, 9 with cardiovascular disea...

introduction: the use of antioxidants before high-intensity training, which leads to the release of free radicals and muscle injuries, can result in reduced damage during exercise. accordingly, in this study, we aimed to evaluate the effect of selenium supplement intake on oxidative stress, following exhaustive aerobic exercise among young physically-active females. methods: in this quasi-exper...

Objective(s):In this study, we aimed at evaluation of electrophysiological and histopathalogical characteristics of statin-induced muscle injury as well as clinical features of patients who develop this condition in terms of frequency and pattern of evolution. Materials and Methods: Forty patients (age 39-74 years) including 25 subjects with type 2 diabetes mellitus, 9 with cardiovascular disea...

Objective(s): Pregabalin (PGB) is a new antiepileptic drug that has received FDA approval for patient who suffers from central neuropathic pain, partial seizures, generalized anxiety disorder, fibromyalgia and sleep disorders. This study was undertaken to evaluate the possible adverse effects of PGB on the muscular system of mice. Materials and Methods: To evaluate the effect of PGB on skeletal...

context hamstring acute muscle injuries are prevalent in several sports including afl football (australian football league), sprinting and soccer, and are often associated with prolonged time away from sport. evidence acquisition in response to this, research into prevention and management of hamstring injury has increased, but epidemiological data shows no decline in injury and re-injury rates...

background and aim: the normal response of h-reflex depression (hd) was reduced in chronic spinal cord injury (sci) patients. the reduction of this normal response can lead to increase the muscle tone and spasticity. the purpose of this study is to investigate the effect of tripolar cathodal stimulation on hd in sci patients.   materials and methods: this study was conducted in 10 volunteered s...

Skeletal muscle injuries are one of the most common problems in the worldwide which impose a substantial financial burden to the health care system.  Accordingly, it widely accepted that muscle regeneration is a promising approach that can be used to treat muscle injury patients. However, the underlying mechanisms of muscle regeneration have yet to be elucidated. The muscle structure and muscle...